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| Status |
Public on Mar 01, 2010 |
| Title |
Gene expression response to implanted drug (paclitaxel)-eluting or bare metal stents in denuded human LIMA arteries |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
[original title] Gene expression response to the implantation of drug (paclitaxel)-eluting or bare metal stents in denuded human LIMA arteries.
Different clinical outcomes have been observed for paclitaxel-eluting and bare metal cardiovascular stents. The aim of this project was to identify genes that might be associated with the observed clinical outcomes.
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| Overall design |
Human left internal mammary artery (LIMA) was divided into three segments and and two of the segments were fitted with either a paclitaxel-eluting stent or a bare metal stent. The experiment includes three groups: control, paclitaxel-eluting stent, and bare metal stent, respectively. Each group includes four biological replicates (patients 1, 2, 4 and 5).
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| Contributor(s) |
Amisten S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Nov 23, 2009 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Ann-Sofie Albrekt |
| E-mail(s) |
ann-sofie.albrekt@immun.lth.se
|
| Phone |
+46462229818
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| Organization name |
Lund University
|
| Street address |
Solvegatan 19
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| City |
Lund |
| ZIP/Postal code |
22184 |
| Country |
Sweden |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (12)
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| GSM474493 |
human_LIMA_artery_patient1_control |
| GSM474494 |
human_LIMA_artery_patient1_bare_metal_cardiovascular_stent |
| GSM474495 |
human_LIMA_artery_patient1_paclitaxel-eluting_stent |
| GSM474496 |
human_LIMA_artery_patient2_control |
| GSM474497 |
human_LIMA_artery_patient2_bare_metal_cardiovascular_stent |
| GSM474498 |
human_LIMA_artery_patient2_paclitaxel-eluting_stent |
| GSM474499 |
human_LIMA_artery_patient4_control |
| GSM474500 |
human_LIMA_artery_patient4_bare_metal_cardiovascular_stent |
| GSM474501 |
human_LIMA_artery_patient4_paclitaxel-eluting_stent |
| GSM474502 |
human_LIMA_artery_patient5_control |
| GSM474503 |
human_LIMA_artery_patient5_bare_metal_cardiovascular_stent |
| GSM474504 |
human_LIMA_artery_patient5_paclitaxel-eluting_stent |
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| Relations |
| BioProject |
PRJNA120751 |
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