|
| Status |
Public on Dec 23, 2021 |
| Title |
A male-derived non-ribosomal peptide pheromone controls female schistosome development II |
| Organism |
Schistosoma mansoni |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
βAlanyl-tryptamine (BATT) is a peptide secreted by male S. mansoni upon pairing with a female parasite. Treatment of synthetic BATT on virgin females wihtout any pairing is sufficient to induce sexual development and egg depostiion.
|
| |
|
| Overall design |
RNA sequencing of virgin female schistosome parasites after 8 days of culturing in ABC169 media supplemented with 5 µM BATT or βAlanine
|
| |
|
| Contributor(s) |
Chen R, Collins JJ |
| Citation(s) |
35385687 |
| |
| Submission date |
Dec 16, 2021 |
| Last update date |
Apr 07, 2022 |
| Contact name |
James J. Collins |
| E-mail(s) |
jamesj.collins@utsouthwestern.edu
|
| Phone |
2143164057
|
| Organization name |
UT Southwestern
|
| Department |
Pharmacology
|
| Street address |
5323 Harry Hines Blvd.
|
| City |
Dallas |
| State/province |
TX |
| ZIP/Postal code |
75390 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL28252 |
NextSeq 550 (Schistosoma mansoni) |
|
| Samples (6)
|
| GSM5738202 |
control virgin females treated with βAla repeat1 |
| GSM5738203 |
control virgin females treated with βAla repeat2 |
| GSM5738204 |
control virgin females treated with βAla repeat3 |
| GSM5738205 |
vrigin females treated with 5 µM BATT repeat1 |
| GSM5738206 |
vrigin females treated with 5 µM BATT repeat2 |
| GSM5738207 |
vrigin females treated with 5 µM BATT repeat3 |
|
| Relations |
| BioProject |
PRJNA789552 |
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