|
| Status |
Public on May 06, 2022 |
| Title |
Core Transcription Programs Controlling Injury-Induced Neurodegeneration of Retinal Ganglion Cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
In this study, we performed RNA-seq of injured and FACS-purified RGCs receiving CRISPR-mediated knockout of ATF3, ATF4, CEBPγ or CHOP
|
| |
|
| Overall design |
We generated RNA-seq data on mouse RGCs receiving control or sgRNA targeting ATF3, ATF4, CEBPγ or CHOP at 3 days following optic nerve injury, with 2-6 replicates in each condition.
|
| |
|
| Contributor(s) |
Cheng Y, Tian F, Geschwind D, He Z |
| Citation(s) |
35767995 |
| Submission date |
Dec 10, 2021 |
| Last update date |
Mar 29, 2024 |
| Contact name |
Yuyan Cheng |
| E-mail(s) |
ycheng316@gmail.com
|
| Organization name |
UCLA
|
| Department |
Neurology
|
| Lab |
Daniel Geschwind
|
| Street address |
695 Charles E Young Dr S Rm 2305
|
| City |
Los Angeles |
| State/province |
CA |
| ZIP/Postal code |
90095 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (21)
|
|
| Relations |
| BioProject |
PRJNA787937 |
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