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| Status |
Public on Jan 23, 2023 |
| Title |
A single cell host/pathogen transcriptome atlas of the HPV16 infected epidermis identifies a novel differentiation-dissonant keratinocyte population implicated in cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report the first single cell transcriptome atlas of HPV16-infected epithelium, describe relevant cell populations and molecular networks as a foundation for antiviral target discovery, and identify a novel differentiation-dissonant keratinocyte population that is implicated in HPV-associated cancer types
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| |
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| Overall design |
Human HPV16 infected keratinocytes were analyzed using 10X single-cell rna-seq
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| |
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| Contributor(s) |
Adam M, Wells S |
| Citation(s) |
37031202 |
| |
| Submission date |
Nov 27, 2021 |
| Last update date |
Apr 24, 2023 |
| Contact name |
Steve Potter |
| Organization name |
Cincinnati Children's Hospital Research Foundation
|
| Department |
Developmental Biology
|
| Street address |
240 Albert Sabin Way
|
| City |
Cincinnati |
| State/province |
Ohio |
| ZIP/Postal code |
45229 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (2) |
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| Relations |
| BioProject |
PRJNA784111 |
| SRA |
SRP348179 |
