|
| Status |
Public on Dec 20, 2021 |
| Title |
Transcriptomic analysis of Aspergillus flavus in response to the solvent Dimethyl Sulfoxide |
| Organism |
Aspergillus flavus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Dimethyl sulfoxide (DSMO) is a simple molecule widely used because of its great solvating ability. Beyond its physico-chemical properties, it is also biologically active, including on fungal species. Aspergillus flavus is a saprophytic and famous pathogenic fungus able to produce Aflatoxin B1 (AFB1), a potent carcinogenic mycotoxin which may contaminate many food crops. The aim of this study was to characterize the effect of DMSO on A. flavus transcriptome profile using high-throughput RNA-sequencing assay.
|
| |
|
| Overall design |
Six replicated fungal mycelium cultures were grown in three conditions (CTRL, DMSO Dose 1, DMSO Dose 2) to generate 18 samples in total which were extracted and processed to perform a RNAseq study.
|
| Web link |
https://doi.org/10.3390/jof7121055
|
| |
|
| Contributor(s) |
Costes LH, Lippi Y, Naylies C, Genthon C, Puel O, Bailly J |
| Citation(s) |
34947037 |
| |
| Submission date |
Nov 19, 2021 |
| Last update date |
Jan 10, 2022 |
| Contact name |
Yannick Lippi |
| E-mail(s) |
yannick.lippi@inrae.fr
|
| Organization name |
INRAE
|
| Department |
GeT-TRiX facility
|
| Lab |
TOXALIM UMR1331
|
| Street address |
180 chemin de tournefeuille
|
| City |
Toulouse |
| ZIP/Postal code |
31300 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL30985 |
Illumina HiSeq 3000 (Aspergillus flavus) |
|
| Samples (18)
|
|
| Relations |
| BioProject |
PRJNA781981 |
| SRA |
SRP346948 |
Less...
More...