|
| Status |
Public on Jan 03, 2022 |
| Title |
Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43 |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We performed bulk RNA-seq on FACS-isolated oligodendrocytes from P30 Mobp-TDP43 and Mog-TDP43 mouse lines to determine the effect of TDP-43 loss at different stages of oligodendrocyte development.
|
| |
|
| Overall design |
Splicing analysis to determine the effect of TDP-43 loss in oligodendrocytes (Mobp-TDP43 Control vs. Mobp-TDP43 KO & Mog-TDP43 Control vs. Mog-TDP43 KO)
|
| |
|
| Contributor(s) |
Heo D, Ling JP, Bergles DE, Kawaguchi R |
| Citation(s) |
35311646 |
| |
| Submission date |
Nov 15, 2021 |
| Last update date |
Apr 05, 2022 |
| Contact name |
Dwight Bergles |
| E-mail(s) |
dbergles@jhmi.edu
|
| Organization name |
Johns Hopkins University
|
| Department |
Neuroscience
|
| Lab |
Dwight Bergles
|
| Street address |
725 North Wolfe St., WBSB 1001
|
| City |
Baltimore |
| State/province |
MD |
| ZIP/Postal code |
21205 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA780585 |
| SRA |
SRP346245 |
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