|
| Status |
Public on May 02, 2022 |
| Title |
RNA-seq analyses of human ameloblastoma and odontogenic keratocyst |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Ameloblastoma (AM) is a benign but locally invasive tumor with high recurrence rates. Invasive behavior of the odontogenic tumor results in destruction of the adjacent jawbone and formation of daughter cysts, hindering the complete elimination of cancer cells during surgery. To understand the underlying mechanism of AM invasion, we compared the transcriptome of AM with that of an odontogenic keratocyst (OKC), a dental epithelium-originated cyst with non-invasive characteristics.
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| |
|
| Overall design |
RNA was extracted from three ameloblastoma and three odontogenic keratocyst tissues collected from individual patients and subjected into RNA-seq anlaysis.
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| |
|
| Contributor(s) |
Kim H, Li S, Jung Y, Jung H |
| Citation(s) |
35794842 |
| |
| Submission date |
Oct 24, 2021 |
| Last update date |
Aug 01, 2022 |
| Contact name |
Han-Sung Jung |
| E-mail(s) |
hsjung@yuhs.ac
|
| Organization name |
Yonsei University
|
| Department |
Dental School
|
| Street address |
50, Yonsei-ro, Seodaemun-gu
|
| City |
Seoul |
| ZIP/Postal code |
03722 |
| Country |
South Korea |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (6)
|
| GSM5653243 |
OKC-1 Human odontogenic keratocyst tissue |
| GSM5653244 |
OKC-3 Human odontogenic keratocyst tissue |
| GSM5653245 |
OKC-4 Human odontogenic keratocyst tissue |
|
| Relations |
| BioProject |
PRJNA774061 |
| SRA |
SRP342915 |
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