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Status |
Public on Mar 17, 2022 |
Title |
Aberrant M1 polarization of macrophages in Behcet’s disease |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Macrophages are key inflammatory immune cells in Behcet’s disease (BD) and BD serum may contribute to macrophages’ hyperactivation in BD. To further investigate the role of BD serum on the phenotypes and functions of macrophages, we performed next generation sequencing-based genome-wide transcriptional profiling on BD serum or healthy control (HC) serum treated macropahges.
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Overall design |
Transcriptional profiling of BD serum treated macropahges (n=4) and HC serum treated macropahges (n=4).
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Contributor(s) |
Wu X, Wang Z, Shi J, Yu X, Li C, Liu J, Zhang F, Chen H, Zheng W |
Citation(s) |
36333776 |
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Submission date |
Oct 14, 2021 |
Last update date |
Nov 17, 2022 |
Contact name |
Wenjie Zheng |
E-mail(s) |
wenjzheng@gmail.com
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Organization name |
Peking Union Medical College Hospital
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Street address |
No1 ShuaiFuYuan,Dong Cheng District ,Beijing, Beijing, CN
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City |
Beijing |
ZIP/Postal code |
100005 |
Country |
China |
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Platforms (1) |
GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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Samples (8)
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Relations |
BioProject |
PRJNA771362 |
SRA |
SRP341413 |