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| Status |
Public on Sep 28, 2021 |
| Title |
Characterization of morphological alterations in micropapillary adenocarcinoma of the lung |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Micropapillary adenocarcinoma of the lung is a cancer with poor prognosis and characterized by the presence of tumor cells with ring-like glandular structure floating within alveolar spaces. We investigated the association between its morphological, biochemical, and immunohistochemical characteristics and malignancy using the KU-Lu-MPPt3 cell line established from a patient with micropapillary adenocarcinoma. Two subpopulations of KU-Lu-MPPt3 cells, adhesive (AD) and clumpy and suspended (CS) cells, were prepared and subjected to DNA microarray.
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| Overall design |
Microarray analysis was performed to investigate the changes in gene expression due to morphological differences in KU-Lu-MPPt3 adhesive (AD) cells and KU-Lu-MPPt3 clumpy and suspended (CS) cells established from the micropapillary adenocarcinoma of the lung. In addition, PC9 which is lung adenocarcinoma cell line was added to the sample.
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| Contributor(s) |
Sonoda D, Matsuo Y, Mikubo M, Satoh Y |
| Citation missing |
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| Submission date |
Sep 27, 2021 |
| Last update date |
Sep 29, 2021 |
| Contact name |
Dai Sonoda |
| E-mail(s) |
dm18015@st.kitasato-u.ac.jp
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| Phone |
08050346023
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| Organization name |
Kitasato University School of Medicine
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| Street address |
1-15-1 Kitasato, Minami-ku
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| City |
Sagamihara |
| State/province |
Kanagawa |
| ZIP/Postal code |
252-0374 |
| Country |
Japan |
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| Platforms (1) |
| GPL23126 |
[Clariom_D_Human] Affymetrix Human Clariom D Assay [transcript (gene) version] |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA766741 |
