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| Status |
Public on Apr 01, 2022 |
| Title |
Deciphering responses of the fetal suprachiasmatic nuclei to the rhythmic maternal signals using omics approach |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We report circadian (time series, circadian time 0, 3, 6, 9, 12, 18, 21h) transcriptomic analysis of mouse fetal (embryonic day 17) suprachiasmatic nuclei (SCN) from either sham operarated ad libitum fed mothers (group A) or from SCN-lesioned mothers on resctricted feeding regime. The analysis revealed low amplitude rhythms in the fetal SCN driven by maternal SCN and/or maternal feeding behavior.
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| Overall design |
Examination of fetal SCN tissue from two groups of mothers on different feeding regime with intact or destroyed cental pacemaker, by RNAseq in a time series
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| Contributor(s) |
Greiner P, Houdek P, Sládek M, Sumová A |
| Citation(s) |
35609026 |
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| Submission date |
Sep 01, 2021 |
| Last update date |
Jun 01, 2022 |
| Contact name |
Martin Sládek |
| E-mail(s) |
sladek@biomed.cas.cz
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| Organization name |
Institute of Physiology of the Czech Academy of Sciences
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| Lab |
Biological rhythms
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| Street address |
Videnska 1083
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| City |
Prague 4 |
| ZIP/Postal code |
142 00 |
| Country |
Czech Republic |
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| Platforms (1) |
| GPL20084 |
Illumina NextSeq 500 (Rattus norvegicus) |
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| Samples (16)
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| GSM5552424 |
8x pooled E17 SCN, maternal SCN after sham surgery, ad libitum fed mother killed at time 0 |
| GSM5552425 |
8x pooled E17 SCN, maternal SCN after sham surgery, ad libitum fed mother killed at time 3 |
| GSM5552426 |
8x pooled E17 SCN, maternal SCN after sham surgery, ad libitum fed mother killed at time 6 |
| GSM5552427 |
8x pooled E17 SCN, maternal SCN after sham surgery, ad libitum fed mother killed at time 9 |
| GSM5552428 |
8x pooled E17 SCN, maternal SCN after sham surgery, ad libitum fed mother killed at time 12 |
| GSM5552429 |
8x pooled E17 SCN, maternal SCN after sham surgery, ad libitum fed mother killed at time 15 |
| GSM5552430 |
8x pooled E17 SCN, maternal SCN after sham surgery, ad libitum fed mother killed at time 18 |
| GSM5552431 |
8x pooled E17 SCN, maternal SCN after sham surgery, ad libitum fed mother killed at time 21 |
| GSM5552432 |
8x pooled E17 SCN, maternal SCN lesion, mother on time-restricted feeding regime killed at time 0 |
| GSM5552433 |
8x pooled E17 SCN, maternal SCN lesion, mother on time-restricted feeding regime killed at time 3 |
| GSM5552434 |
8x pooled E17 SCN, maternal SCN lesion, mother on time-restricted feeding regime killed at time 6 |
| GSM5552435 |
8x pooled E17 SCN, maternal SCN lesion, mother on time-restricted feeding regime killed at time 9 |
| GSM5552436 |
8x pooled E17 SCN, maternal SCN lesion, mother on time-restricted feeding regime killed at time 12 |
| GSM5552437 |
8x pooled E17 SCN, maternal SCN lesion, mother on time-restricted feeding regime killed at time 15 |
| GSM5552438 |
8x pooled E17 SCN, maternal SCN lesion, mother on time-restricted feeding regime killed at time 18 |
| GSM5552439 |
8x pooled E17 SCN, maternal SCN lesion, mother on time-restricted feeding regime killed at time 21 |
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| Relations |
| BioProject |
PRJNA759558 |
| SRA |
SRP335186 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE183172_Counts.csv.gz |
579.3 Kb |
(ftp)(http) |
CSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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