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| Status |
Public on Aug 28, 2021 |
| Title |
RNAseq of mRNA from murine small intestinal crypts |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Spontaneous inflammation in the terminal ileum of Xiap–/– mice was observed to occur in a microbiome dependent manner. Xiap–/– mice housed alone presented with signs of inflammation which were alleviated upon co-housing the mice with wild-type counterparts. To elucidate the impact of co-housing, and thus the transfer of the microbiome to affected Xiap–/– mice, crypts from the small intestine of these mice were analyzed.
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| Overall design |
Small intestinal crypts from wild-type and Xiap-deficient mice either housed according to genotype or co-housed together for four weeks were isolated and subjected to RNA-seq analysis.
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| Contributor(s) |
Yabal M, Donakonda S, Oellinger R, Engleitner T |
| Citation(s) |
34739338 |
| |
| Submission date |
Aug 27, 2021 |
| Last update date |
Nov 11, 2021 |
| Contact name |
Monica Yabal |
| Organization name |
Technical University of Munich
|
| Street address |
Ismaninger straße 22
|
| City |
Munich |
| ZIP/Postal code |
81675 |
| Country |
Germany |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (20)
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| Relations |
| BioProject |
PRJNA758379 |
| SRA |
SRP334474 |
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