|
| Status |
Public on Jul 07, 2024 |
| Title |
ac4C RIP-seq analysis of AGS cells upon NAT10 knockout. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Other
|
| Summary |
N4-acetylcytidine (ac4C), a conserved chemical modification in eukaryotic prokaryotes that is catalyzed by the N-acetyltransferase 10 (NAT10) enzyme, plays a crucial role in promoting mRNA stability and translation. However, the biological function and mechanisms of NAT10-mediated ac4C in human cancer were poorly defined. In order to investigate the regulatory mechanism of NAT10 in gastric cancer, we performed ac4C RIP-seq(acRIP-seq) analysis in AGS cells with NAT10 knockout compared with control in two repeats.
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| |
|
| Overall design |
Identification of the downstream targets of NAT10 by acRIP-seq analysis in AGS cells upon NAT10 knockout
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| |
|
| Contributor(s) |
Deng M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jul 20, 2021 |
| Last update date |
Jul 07, 2024 |
| Contact name |
Min Deng |
| E-mail(s) |
mindeng@gzhmu.edu.cn
|
| Phone |
13924307478
|
| Organization name |
Affiliated Cancer Hospital & Institute of Guangzhou Medical University
|
| Street address |
Affiliated Cancer Hospital & Institute of Guangzhou Medical University, NO.78, Hengzhigang Road.
|
| City |
GUANGZHOU |
| State/province |
GUANGDONG |
| ZIP/Postal code |
510095 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (8)
|
| GSM5463931 |
Gastric adenocarcinoma cells - AGS CTR-1 Input |
| GSM5463932 |
Gastric adenocarcinoma cells - AGS CTR-1 IP |
| GSM5463933 |
Gastric adenocarcinoma cells - AGS CTR-2 Input |
| GSM5463934 |
Gastric adenocarcinoma cells - AGS CTR-2 IP |
| GSM5463935 |
Gastric adenocarcinoma cells - AGS NAT10 KO-1 Input |
| GSM5463936 |
Gastric adenocarcinoma cells - AGS NAT10 KO-1 IP |
| GSM5463937 |
Gastric adenocarcinoma cells - AGS NAT10 KO-2 Input |
| GSM5463938 |
Gastric adenocarcinoma cells - AGS NAT10 KO-2 IP |
|
| Relations |
| BioProject |
PRJNA748414 |
| SRA |
SRP329145 |
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