|
| Status |
Public on Sep 24, 2021 |
| Title |
Selective Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibition by the SCH772984 Compound Attenuates In Vitro and In Vivo Inflammatory Responses and Prolongs Survival in Murine Sepsis Models |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
This is an accompanying ATAC-seq data to the transcriptomic survey of RAW264.7 cells treated with ERK1/2 inhibitor SCH772984 upon 1hr, 4hrs and 24 hrs LPS challenge. The transcriptomic data are deposited in GEO under GSE179554.
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| |
|
| Overall design |
The experiment was performed on two independent biological replicates per treatment. 16 samples are included.
|
| Web link |
https://www.mdpi.com/1422-0067/22/19/10204
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| |
|
| Contributor(s) |
Kopczyński M, Rumieńczyk I, Kulecka M, Statkiewicz M, Mikula M |
| Citation(s) |
34638546 |
| |
| Submission date |
Jul 14, 2021 |
| Last update date |
Oct 26, 2021 |
| Contact name |
Michał Mikula |
| E-mail(s) |
mikula.michal@gmail.com
|
| Phone |
+48225462655
|
| Organization name |
Maria Skłodowska-Curie National Research Institute of Oncology
|
| Department |
Genetics
|
| Street address |
Roentgena 5
|
| City |
Warsaw |
| ZIP/Postal code |
02781 |
| Country |
Poland |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (16)
|
|
| Relations |
| BioProject |
PRJNA746487 |
| SRA |
SRP328299 |
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