|
| Status |
Public on Mar 08, 2022 |
| Title |
Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers [ATAC HD] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
ATAC-seq was used to study the chromatin landscape of T cell subsets from PBMCs healthy donors.
|
| |
|
| Overall design |
CD8 and CD4 Immune cell subsets were sorted from young and older healthy donors PBMC samples and chromatin accessibility was assayed for comparison across age and between various Immune cell subsets
|
| Web link |
https://doi.org/10.1016/j.immuni.2022.02.004
|
| |
|
| Contributor(s) |
Giles J, Manne S, Wherry EJ |
| Citation(s) |
35263570 |
| |
| Submission date |
Jul 06, 2021 |
| Last update date |
Aug 02, 2022 |
| Contact name |
E JOHN WHERRY |
| Organization name |
University of Pennsylvania
|
| Department |
Systems Pharmacology and Translational Therapeutics,Institute for Immunology
|
| Street address |
421 Curie Blvd,354 BRB II/III
|
| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (217)
|
|
| This SubSeries is part of SuperSeries: |
| GSE179613 |
Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers |
|
| Relations |
| BioProject |
PRJNA744248 |
| SRA |
SRP327212 |
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