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| Status |
Public on Apr 06, 2022 |
| Title |
RNA sequencing of the spleen of naked mole-rat and mouse |
| Organisms |
Mus musculus; Heterocephalus glaber |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Heathly naked mole-rats kept under normal housing conditions harbor either a small or enlarged spleen. The aim of the study is to compare RNAseq of naked mole-rat (NM-R) small and enlarged spleens between them and to compare them with RNAseq of mouse spleen.
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| Overall design |
Dissection of the spleen from NM-R and mice kept under normal housekeeping conditions. We observed that healthy NM-R have either small or enlarged spleen. We therefore compared 3 groups: NM-R with small spleen, NM-R with enlarged spleen and mouse spleen, n = 3 per group. After extraction of total RNA, RNA sequencing and transcriptome analysis were performed. RNA was sequenced on the Illumina NovaSeq6000 Platform.
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| Contributor(s) |
Valérie B, Branko C, Lewin G |
| Citation(s) |
35382566 |
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Begay et al. Open Biol. 12: 210292. https://doi.org/10.1098/rsob.210292
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| Submission date |
Jul 02, 2021 |
| Last update date |
Apr 19, 2022 |
| Contact name |
Valerie Begay |
| E-mail(s) |
vbegay@mdc-berlin.de
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| Organization name |
Max Delbrück Center
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| Street address |
Robert-Rössle-Str. 10
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| City |
Berlin |
| ZIP/Postal code |
13125 |
| Country |
Germany |
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| Platforms (2) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
| GPL21195 |
Illumina HiSeq 2500 (Heterocephalus glaber) |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA743323 |
| SRA |
SRP326684 |
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