|
| Status |
Public on Jul 27, 2021 |
| Title |
Impaired Right Ventricular Calcium Cycling Is an Early Risk 2 Factor in R14del-Phospholamban Arrhythmias |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We utilized humanized wild-type and R14 deletion (R14del) phospholamban (PLN) knock-in mice to determine the role of the inherited PLN-R14del on malignant right ventricular arrhythmias.
|
| |
|
| Overall design |
RNA-seq to determine global gene expression profiles in LV and RV samples from humanized WT and R14del mutant mouse hearts
|
| |
|
| Contributor(s) |
Tranter M, Kranias L |
| Citation(s) |
34204946, 36375644 |
| |
| Submission date |
May 01, 2021 |
| Last update date |
Nov 17, 2022 |
| Contact name |
Michael Tranter |
| E-mail(s) |
Michael.tranter@osumc.edu
|
| Organization name |
The Ohio State University
|
| Department |
Molecular Medicine and Therapeutics
|
| Street address |
2255 Kenny Road
|
| City |
Columbus |
| State/province |
OH |
| ZIP/Postal code |
43210 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA726640 |
| SRA |
SRP318085 |
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