NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE172365 Query DataSets for GSE172365
Status Public on Jun 01, 2021
Title Multi-omics co-localization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus [Methylation array]
Organism Homo sapiens
Experiment type Methylation profiling by array
Summary We generated genome-wide DNA methylation data from cultured airway epithelial cells exposed to rhinovirus (RV) and a vehicle control (48 hour treatment). This data was generated in combination with genome-wide expression data (RNAseq) and genotypes from the same individuals.
 
Overall design Identification of DNA methylation quantitative trait loci (meQTLs) in vehicle- and RV-treated airway epithelial cells, and colocalization with childhood onset and adult onset GWASs.
 
Contributor(s) Soliai MM, Wentworth-Sheilds W
Citation(s) 34629083
Submission date Apr 19, 2021
Last update date Nov 03, 2021
Contact name Carole Ober
E-mail(s) c-ober@genetics.uchicago.edu
Organization name The University of Chicago
Department Human Genetics
Lab Ober
Street address 920 E 58TH ST
City Chicago
State/province IL
ZIP/Postal code 60637
Country USA
 
Platforms (1)
GPL21145 Infinium MethylationEPIC
Samples (206)
GSM5253220 genomic DNA from cultured airway epithelial cells (basal cells) [76b3_439a-1A]
GSM5253221 genomic DNA from cultured airway epithelial cells (basal cells) [76b3_439a-2A]
GSM5253222 genomic DNA from cultured airway epithelial cells (basal cells) [db6c_413d-1A]
This SubSeries is part of SuperSeries:
GSE172368 Multi-omics co-localization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus
Relations
BioProject PRJNA723034

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE172365_RAW.tar 3.0 Gb (http)(custom) TAR (of IDAT)
GSE172365_crisprv.meth.matrix.processed.txt.gz 1.7 Gb (ftp)(http) TXT
GSE172365_matrix.signal.intensities.txt.gz 1.1 Gb (ftp)(http) TXT
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap