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Status |
Public on Apr 29, 2024 |
Title |
RNAseq of mRNA from splenic and hepatic CD8 T cell populations after resolved and during persistent AdV infection |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
We aimed at dissecting phenotype, functionality and regulation of antigen-specific hepatic and splenic CX3CR1-positive and hepatic CXCR6-positive CD8 T cells after resolved or during persistent viral infection of the liver.
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Overall design |
Comparison of splenic and hepatic CD8 T cell populations in two infection models (n=3 for each sample group). For resolved infection, hepatic T cells were sorted into CXCR6 and CX3CR1 populations. For persistent infection, hepatic T cells were sorted into CXCR6 and CXCR6-CX3CR1 populations.
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Contributor(s) |
Bosch M, Kallin N, Donakonda S, Oellinger R, Engleitner T, Knolle PA |
Citation(s) |
38987588 |
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Submission date |
Mar 02, 2021 |
Last update date |
Aug 11, 2024 |
Contact name |
sainitin donakonda |
E-mail(s) |
saigro16@gmail.com
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Organization name |
TUM
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Department |
Institute of Immunology
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Lab |
Höchst lab
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Street address |
Ismaningerstr. 22
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City |
München |
State/province |
Bavaria |
ZIP/Postal code |
81675 |
Country |
Germany |
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Platforms (1) |
GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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Samples (15)
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Relations |
BioProject |
PRJNA706019 |
SRA |
SRP308914 |