|
| Status |
Public on Feb 18, 2021 |
| Title |
Interleukin-17 governs hypoxic adaptation of injured epithelium [spatial transcriptomics] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To define the gene signature and spatial architecture of the skin after injury, we performed spatial transcriptomics from mouse unwounded and wounded skin.
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| |
|
| Overall design |
Wild type (unwounded, wounded) and GFP-KI (wounded) skin were fresh frozen and sectioned at 10um thickness onto spatial transcriptomics (ST) slides for mRNA capture, followed by library preparation and sequencing. The GFP-KI genotype disrupts the Rorc gene.
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| |
|
| Contributor(s) |
Konieczny P, Yue X, Sidhu I, Naik S |
| Citation(s) |
35709248 |
| |
| Submission date |
Feb 17, 2021 |
| Last update date |
Jan 05, 2023 |
| Contact name |
Shruti Naik |
| E-mail(s) |
Shruti.Naik@nyulangone.org
|
| Organization name |
NYU Langone Health
|
| Department |
Pathology
|
| Lab |
Naik Lab
|
| Street address |
435 East 30th Street
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10016 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (6)
|
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| This SubSeries is part of SuperSeries: |
| GSE166950 |
Interleukin-17 governs hypoxic adaptation of injured epithelium |
|
| Relations |
| BioProject |
PRJNA702458 |
| SRA |
SRP306848 |
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