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| Status |
Public on Mar 01, 2021 |
| Title |
Altered hippocampal transcriptome dynamics following sleep deprivation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Purpose: To comprehensively identify the gene expression changes that occur after acute sleep deprivation.
Method: We performed total RNA sequencing after 5hours of sleep deprivation.
Results: Using total RNA-sequencing, we show that acute sleep deprivation causes dramatic gene expression changes in the mouse hippocampus.
Conclusion: This study provides insight into the biological impact of acute sleep deprivation.
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| |
|
| Overall design |
Whole hippocampus RNA profiles of 2-4 months old male C57Bl/6J mice who were either sleep deprived for 5hours or left undisturbed.
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| |
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| Contributor(s) |
Gaine ME, Bahl E, Chatterjee S, Michaelson JJ, Abel T, Lyons LC |
| Citation(s) |
34384474 |
| |
| Submission date |
Feb 16, 2021 |
| Last update date |
Aug 24, 2021 |
| Contact name |
Ethan Bahl |
| E-mail(s) |
ethan-bahl@uiowa.edu
|
| Organization name |
University of Iowa
|
| Street address |
25 S Grand Ave
|
| City |
Iowa City |
| State/province |
IA |
| ZIP/Postal code |
52242 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (18)
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| Relations |
| BioProject |
PRJNA702096 |
| SRA |
SRP306643 |
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