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| Status |
Public on Mar 06, 2021 |
| Title |
Super Enhancer Regulation of Cytokine-Induced Chemokine Production in Alcoholic Hepatitis [ChIP-Seq 3] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Super enhancer in liver propagates inflammatory signaling by super enhancer-mediatedinducing chemokine expression and is the therapeutic potential of BET inhibition in Alcoholic hepatitis(AH) treatment.
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| |
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| Overall design |
For human liver sinusoid endothelial cell (LSEC) ChIP-Seq analyses, control and TNF treated LSECs are collected to perfrom ChIPseq with anti H3k27ac and NFKB antibodies respectively.
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| |
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| Contributor(s) |
Shah VH, Cao S, Liu M |
| Citation missing |
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| |
| Submission date |
Feb 10, 2021 |
| Last update date |
Mar 08, 2021 |
| Contact name |
Aditya Bhagwate |
| E-mail(s) |
bhagwate.adityavijay@mayo.edu
|
| Organization name |
Mayo Clinic
|
| Street address |
200 1st Street SW
|
| City |
Rochester |
| State/province |
MN |
| ZIP/Postal code |
55905 |
| Country |
USA |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA701278 |
| SRA |
SRP305714 |
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