|
| Status |
Public on Feb 08, 2024 |
| Title |
CDK12 maintains phosphorylation of RNA Polymerase II during epidermal differentiation |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
|
| Summary |
CDK12 plays an important role in regulating epidermal differntaition through maintaining the phosphorylation of RNA polymerase II levels in differentiation associated genes.
|
| |
|
| Overall design |
CDK12 knockdown RNA-Seq in calcium induced differentiated primary keratinocytes. CDK12 ChIP-Seq with CDK12 and RNA Pol II antibodies in calcium induced differentiated primary keratinocytes.
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| |
|
| Contributor(s) |
Li J, Sen G |
| Citation(s) |
35325240 |
| |
| Submission date |
Feb 09, 2021 |
| Last update date |
May 09, 2024 |
| Contact name |
Jingting Li |
| E-mail(s) |
lijt66@mail.sysu.edu.cn
|
| Organization name |
The First Affiliated Hospital, Sun Yat-sen University
|
| Department |
Institue of Precision Medicine
|
| Street address |
No 1, Zhongshan 2 Road, 12th Floor
|
| City |
Guangzhou |
| ZIP/Postal code |
510080 |
| Country |
China |
| |
|
| Platforms (2) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA700840 |
| SRA |
SRP305468 |
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