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| Status |
Public on Jun 15, 2021 |
| Title |
Poor Endometrial Proliferation after Clomiphene is Associated with Altered Estrogen Action [ChIP-Seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We report ESR1 cistromic profiles from endometrial biopsies obtained from infertile women in the late proliferative phase who developed either optimal (≥8mm) or suboptimal (<6mm) endometrial thickness following early follicular phase exposure to 100mg clomiphene citrate for 5 days.
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| Overall design |
ESR1 ChIP-seq was conducted on whole endometrium during the late proliferative phase. In parallel, RNA-seq analyses were conducted on whole endometrium during the late proliferative phase.
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| Contributor(s) |
Bressler LH, Fritz MA, Wu S, Yuan L, Kafer S, Wang T, DeMayo FJ, Young SL |
| Citation(s) |
34058008 |
| |
| Submission date |
Jan 13, 2021 |
| Last update date |
Jun 30, 2022 |
| Contact name |
Franco Demayo |
| E-mail(s) |
francesco.demayo@nih.gov
|
| Organization name |
NIEHS
|
| Street address |
111 TW Alexander Drive
|
| City |
RTP |
| State/province |
NC |
| ZIP/Postal code |
27709 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (5)
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| This SubSeries is part of SuperSeries: |
| GSE164769 |
Poor Endometrial Proliferation after Clomiphene is Associated with Altered Estrogen Action |
|
| Relations |
| BioProject |
PRJNA692048 |
| SRA |
SRP301827 |
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