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Series GSE1642 Query DataSets for GSE1642
Status Public on Sep 01, 2004
Title Transcriptional Responses of M. tuberculosis to inhibitors of metabolism
Platform organism Mycobacterium tuberculosis
Sample organism Mycobacterium tuberculosis H37Rv
Experiment type Expression profiling by array
Summary Transcriptional profiling of M.tuberculosis was performed using 430 whole-genome microarrays to measure the effects of 75 different drugs, drug combinations or different growth conditions at various times relative to a sample of logarithmically growing MTb. Analysis of this data set revealed 150 underlying clusters of coordinately regulated genes as described in Boshoff et al., 2004.
Keywords = Gene clusters
Keywords = Mechanism of action
Keywords = tuberculosis
Keywords = antimycobacterial drugs
Keywords = natural product
Keywords = respiration
Keywords: other
 
 
Contributor(s) Boshoff HI, Myers TG, Copp BR, McNeil MR, Wilson MA, Barry CE
Citation(s) 15247240
Submission date Aug 04, 2004
Last update date Mar 15, 2012
Contact name Helena I Boshoff
E-mail(s) hboshoff@niaid.nih.gov
Phone 301-451-9438
Fax 301-402-0993
Organization name NIAID/ NIH
Department LIG
Lab Tuberculosis Research Section
Street address 12441 Parklawn Drive
City Rockville
State/province MD
ZIP/Postal code 20852
Country USA
 
Platforms (2)
GPL1343 NIAID Mycobacterium tuberculosis microarray Mtbb
GPL1396 NIAID - Mta[a,b,c]
Samples (437)
GSM27855 0.1ug/mL Mtm:ctrl (0.33h) ( mAdb expid=24065 )
GSM27856 0.2ug/mL Mtm:ctrl (0.33h) ( mAdb expid=24066 )
GSM27857 0.1ug/mL Mtm:ctrl (0.75h) ( mAdb expid=24067 )
Relations
BioProject PRJNA90691

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