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Series GSE164127 Query DataSets for GSE164127
Status Public on Jan 28, 2021
Title Genome Methylation Predicts Age and Longevity of Bats
Platform organisms Homo sapiens; Mus musculus; Rattus norvegicus
Sample organisms Pteropus poliocephalus; Pteropus hypomelanus; Rousettus aegyptiacus; Artibeus jamaicensis; Phyllostomus hastatus; Desmodus rotundus; Tadarida brasiliensis; Antrozous pallidus; Molossus molossus; Nycticeius humeralis; Eptesicus fuscus; Carollia perspicillata; Myotis myotis; Nyctalus noctula; Cynopterus brachyotis; Myotis lucifugus; Rhinolophus ferrumequinum; Saccopteryx bilineata; Eidolon helvum; Pteropus rodricensis; Phyllostomus discolor; Myotis brandtii; Pteropus vampyrus; Pteropus giganteus; Pteropus pumilus; Myotis vivesi; Rhynchonycteris naso; Leptonycteris yerbabuenae
Experiment type Methylation profiling by array
Summary An Infinium microarray platform (GPL28271, HorvathMammalMethylChip40) was used to generate DNA methylation data from several tissues in several bat species.
Tissues: skin (wing punches), liver, brain, skeletal muscle.
 
Overall design N=860 tissue samples from 28 different bat species were profiled on the mammalian methylation array platform (GPL28271). N=796 of these samples come from wing punches (skin tissue). The remaining samples come from brain (N=9), liver (N=17), muscle (N=17). Due to quality issues N=28 samples were omitted from the analysis, see the characteristic variable CanBeUsedForAgingStudies. We profiled samples from 28 different bat species whose Latin names are as follows: Antrozouspallidus, Artibeusjamaicensis, Carolliaperspicillata, Cynopterusbrachyotis, Desmodusrotundus, Eidolonhelvum, Eptesicusfuscus, Leptonycterisyerbabuenae, Molossusmolossus, Myotisbrandtii, Myotislucifugus, Myotismyotis, Myotisvivesi, Nyctalusnoctula, Nycticeiushumeralis, Phyllostomusdiscolor, Phyllostomushastatus, Pteropusgiganteus, Pteropushypomelanus, Pteropuspoliocephalus, Pteropuspumilus, Pteropusrodricensis, Pteropusvampyrus, Rhinolophusferrumequinum, Rhynchonycterisnaso, Rousettusaegyptiacus, Saccopteryxbilineata, Tadaridabrasiliensis. Gene annotations for the microarray for ten bat genomes are available from the Digital Repository at the University of Maryland (DRUM) at http://hdl.handle.net/1903/26373 .
N=48 wing punch samples from different bat species were profiled on the mammalian methylation array platform (GPL28271). We profiled samples from different bat species whose Latin names are as follows: Eptesicus fuscus, Phyllostomus hastatus, Carollia perspicillata. Gene annotations for the microarray for ten bat genomes are available from the Digital Repository at the University of Maryland (DRUM) at http://hdl.handle.net/1903/26373 .
Web link https://pubmed.ncbi.nlm.nih.gov/33712580/
 
Contributor(s) Horvath S, Wilkinson GS
Citation(s) 33712580, 35145108, 37563227, 38848365
Submission date Dec 31, 2020
Last update date Jun 26, 2024
Contact name Steve Horvath
E-mail(s) shorvath@altoslabs.com
Organization name University of California, Los Angeles
Department Human Genetics
Lab Horvath
Street address 695 Charles E. Young Drive South, Box 708822
City Los Angeles
State/province CA
ZIP/Postal code 90095-7088
Country USA
 
Platforms (1)
GPL28271 Illumina HorvathMammalianMethylChip40 BeadChip
Samples (908)
GSM4997095 Sample1.Variable flying fox.202897220086_R01C01
GSM4997096 Sample2.Large flying fox.202897220086_R02C01
GSM4997097 Sample3.Variable flying fox.202897220086_R03C01
Relations
BioProject PRJNA688932

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE164127_Explanation_of_characteristic_variables.docx.gz 13.5 Kb (ftp)(http) DOCX
GSE164127_RAW.tar 678.2 Mb (http)(custom) TAR (of IDAT)
GSE164127_readme.txt 1.4 Kb (ftp)(http) TXT
Processed data included within Sample table
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