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| Status |
Public on Mar 15, 2021 |
| Title |
miRNA profile of plasma samples from Plasmodium vivax malaria patients and healthy subjects |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
Severe thrombocytopenia can be a determinant factor in the morbidity of Plasmodium vivax (Pv), the most widespread human malaria. Although immune mechanisms may drive Pv-induced severe thrombocytopenia (PvST), the current data on the cytokine landscape in PvST is scarce, and often conflicting. The analysis of the bidirectional circuit of inflammatory mediators and miRNAs would lead to a better understanding of the mechanisms underlying PvST.
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| Overall design |
Unique samples from 34 subjects, including Plasmodium vivax malaria patients (n=26) and healthy subjects (n=8) were included in the study.
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| Contributor(s) |
Santos M, Franklin B |
| Citation(s) |
33791239 |
| |
| Submission date |
Nov 29, 2020 |
| Last update date |
Apr 07, 2021 |
| Contact name |
Luzia Helena Carvalho |
| Organization name |
Instituto René Rachou, FIOCRUZ
|
| Street address |
Av. Augusto de Lima, 1715
|
| City |
Belo Horizonte |
| State/province |
Minas Gerais |
| ZIP/Postal code |
30190-002 |
| Country |
Brazil |
| |
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| Platforms (1) |
| GPL28943 |
NanoString nCounter Human v3 miRNA Expression Assay |
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| Samples (34)
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| Relations |
| BioProject |
PRJNA681398 |
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