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| Status |
Public on Jul 19, 2022 |
| Title |
Thyroid hormone receptor α controls larval intestinal epithelial cell death by regulating the CDK1 pathway |
| Organism |
Xenopus tropicalis |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Our study represents the first detailed analysis of thyroid hormone binding to the genome in the intestine of wild-type and TRα (-/-) tadpoles, with biological replicates, generated by ChIP-seq technology. The optimized data analysis workflows reported here should provide a framework for comparative investigations of TR binding profiles.
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| |
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| Overall design |
Examination of 3 technical replicates from the same ChIP-DNA sample which extracted and merged from the several Xenopus tropicalis tadpoles.
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| |
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| Contributor(s) |
Tanizaki Y, Shi Y, Zhang H |
| Citation(s) |
35132135 |
| |
| Submission date |
Nov 18, 2020 |
| Last update date |
Mar 16, 2023 |
| Contact name |
Ryan Dale |
| E-mail(s) |
dalerr@nih.gov
|
| Organization name |
National Institutes of Health
|
| Department |
National Institute of Child Health and Human Development
|
| Lab |
Bioinformatics and Scientific Programming Core
|
| Street address |
Rm 10D39, 10 Center Drive
|
| City |
Bethesda |
| State/province |
MD |
| ZIP/Postal code |
20892 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL21875 |
Illumina HiSeq 2500 (Xenopus tropicalis) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA679246 |
| SRA |
SRP293094 |
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