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| Status |
Public on Jun 01, 2021 |
| Title |
Expression data from adult male mouse hypothalamus |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Laser captured regions surrounding the perifornical area (PeFA) in adult male mice that attacked pups; a control outside region (unk); a c-fos positive region (c-fos); an oxytocin positive region (oxt)
In this dataset, we include the expression data obtained from dissected mouse forelimbs using a variety of gain- and loss-of-function hedgehog pathway mutants, as well as limbs dissected into responsive (posterior 2/3ds) and non-responsive (anterior 1/3d) Hh tissues. These data are used to obtain 753 genes that are differentially expressed in response to Shh signaling.
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| Overall design |
We obtained 3 biological replicates containing pooled tissue from 6 males for each specified laser-captured area (n=18 total). C-fos, oxytocin, and outside regions were obtained from the same samples such that the samples are paired observations (Sample 1, sample 2, sample 3 are the names of the 3 replicates of pooled samples).
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| |
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| Contributor(s) |
Autry AE, Tang M |
| Citation(s) |
34423776 |
| |
| Submission date |
Nov 15, 2020 |
| Last update date |
Aug 31, 2021 |
| Contact name |
Anita E Autry |
| E-mail(s) |
anita.autry@einsteinmed.edu
|
| Organization name |
Albert Einstein College of Medicine
|
| Department |
Neuroscience and Psychiatry
|
| Lab |
Autry
|
| Street address |
1410 Pelham Parkway S
|
| City |
Bronx |
| State/province |
NY |
| ZIP/Postal code |
10706 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL6096 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [transcript (gene) version] |
|
| Samples (9)
|
| GSM4908906 |
C-fos positive region collected from sample 1 |
| GSM4908907 |
C-fos positive region collected from sample 2 |
| GSM4908908 |
C-fos positive region collected from sample 3 |
| GSM4908909 |
Oxt positive region collected from sample 1 |
| GSM4908910 |
Oxt positive region collected from sample 2 |
| GSM4908911 |
Oxt positive region collected from sample 3 |
| GSM4908912 |
Unknown outside region collected from sample 1 |
| GSM4908913 |
Unknown outside region collected from sample 2 |
| GSM4908914 |
Unknown outside region collected from sample 3 |
|
| Relations |
| BioProject |
PRJNA678554 |
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