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Series GSE160852 Query DataSets for GSE160852
Status Public on Feb 25, 2021
Title Transcriptional profiling of fission yeast RNA polymerase II CTD mutants
Organism Schizosaccharomyces pombe
Experiment type Expression profiling by high throughput sequencing
Summary This RNA-Seq analysis compares gene expression of the RNA polymerase II CTD-mutants contrasting to the WT RNA polymerase II CTD (with isogenic 3' selection marker) in the fission yeast S. pombe
Overall design 8 test samples were analyzed, of which rpb1-CTD-T4A29 was previously submitted under GEO accession number GSE155609; 2 parental control samples (rpb1-CTD-WT29) were processed (each control set indicates which test samples were compared). Each sample has at least 3 replicate experiments.

rpb1-CTD-WT18 [truncated CTD with 18 consensus repeats] has 4 replicates where two replicates processed were deposited under GEO accession no. GSE52370)
Contributor(s) Garg A, Schwer B, Shuman S
Citation(s) 33579781
NIH grant(s)
Grant ID Grant title Affiliation Name
R35 GM126945 Mechanisms of DNA and RNA transactions Sloan Kettering Institute for Cancer Research Stewart H Shuman
R01 GM052470 Deciphering the RNA Polymerase II CTD Code Sloan Kettering Institute for Cancer Research BEATE SCHWER
R01 GM134021 Inositol pyrophosphate dynamics affect RNA 3'-processing/transcription termination WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY BEATE SCHWER
Submission date Nov 04, 2020
Last update date Sep 16, 2021
Contact name Angad Garg
Organization name Memorial Sloan Kettering Cancer Center
Department Molecular Biology
Lab Stewart Shuman
Street address RRL-865 430 E 67th St.
City New York
State/province New York
ZIP/Postal code 10065
Country USA
Platforms (2)
GPL13988 Illumina HiSeq 2000 (Schizosaccharomyces pombe)
GPL28961 Illumina NovaSeq 6000 (Schizosaccharomyces pombe)
Samples (29)
GSM4880425 h+ rpb1-CTD-WT29::NatMX [WT1]
GSM4880426 h+ rpb1-CTD-WT29::NatMX [WT2]
GSM4880427 h+ rpb1-CTD-WT29::NatMX [WT3]
BioProject PRJNA674640
SRA SRP291182

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE160852_CTD_count_matrix_updated.txt.gz 390.5 Kb (ftp)(http) TXT
GSE160852_DESeq2_ALT_P3A_vs_markWT.xlsx 1.2 Mb (ftp)(http) XLSX
GSE160852_DESeq2_ALT_P6A_vs_markWT.xlsx 1.2 Mb (ftp)(http) XLSX
GSE160852_DESeq2_ALT_S5A_vs_markWT.xlsx 1.1 Mb (ftp)(http) XLSX
GSE160852_DESeq2_T4A_vs_markWT.xlsx 1.2 Mb (ftp)(http) XLSX
GSE160852_S2A_S7A_v_markWT_DESeq2.xlsx 1.1 Mb (ftp)(http) XLSX
GSE160852_S2A_v_markWT_DESeq2.xlsx 1.1 Mb (ftp)(http) XLSX
GSE160852_Y1F_v_markWT_DESeq2.xlsx 1.1 Mb (ftp)(http) XLSX
GSE160852_rpb1-18_v_markWT_DESeq2.xlsx 950.4 Kb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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