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Series GSE159886 Query DataSets for GSE159886
Status Public on Feb 21, 2022
Title Epigenome of ASXL1-mutant and ASXL1-wildtype chronic myelomonocytic leukemia
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Methylation profiling by high throughput sequencing
Summary We report the chromatin characteristics of human chronic myelomonocytic leukemia by performing chromatin immunoprecipitation sequencing of histone modifications (ChIP-seq), immunoprecipitation sequencing of (hydroxy-)methylated residues (DIP-seq), and transposase accessibility sequencing (ATAC-seq) of bone marrow mononuclear cells of patients with chronic myelomonocytic leukemia.
 
Overall design Comparison of chromatin characteristics between ASXL1-mutant and ASXL1-wildtype chronic myelomonocytic leukemia.
 
Contributor(s) Patnaik MM
Citation(s) 35301312
Submission date Oct 22, 2020
Last update date Jun 26, 2023
Contact name Mrinal M. Patnaik
Organization name Mayo Clinic
Department Division of Hematology
Street address 200 First Street SW
City Rochester
State/province MN
ZIP/Postal code 55905
Country USA
 
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (154)
GSM5720191 Human bone marrow mononuclear cells, 5hmC Sample 01
GSM5720192 Human bone marrow mononuclear cells, 5hmC Sample 02
GSM5720193 Human bone marrow mononuclear cells, 5hmC Sample 03
Relations
BioProject PRJNA670720
SRA SRP288190

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE159886_ASXL1_MT_5hmC_Consensus_Peaks.bw 3.8 Mb (ftp)(http) BW
GSE159886_ASXL1_MT_5mC_Consensus_Peaks.bw 3.8 Mb (ftp)(http) BW
GSE159886_ASXL1_MT_ATAC_Consensus_Peaks.bw 745.3 Kb (ftp)(http) BW
GSE159886_ASXL1_MT_ChromHMM_States.bw 2.8 Mb (ftp)(http) BW
GSE159886_ASXL1_MT_H2AK119ub_Consensus_Peaks.bw 291.0 Kb (ftp)(http) BW
GSE159886_ASXL1_MT_H3K27ac_Consensus_Peaks.bw 811.1 Kb (ftp)(http) BW
GSE159886_ASXL1_MT_H3K27me3_Consensus_Peaks.bw 141.9 Kb (ftp)(http) BW
GSE159886_ASXL1_MT_H3K4me1_Consensus_Peaks.bw 316.9 Kb (ftp)(http) BW
GSE159886_ASXL1_MT_H3K4me3_Consensus_Peaks.bw 361.9 Kb (ftp)(http) BW
GSE159886_ASXL1_WT_5hmC_Consensus_Peaks.bw 3.7 Mb (ftp)(http) BW
GSE159886_ASXL1_WT_5mC_Consensus_Peaks.bw 3.7 Mb (ftp)(http) BW
GSE159886_ASXL1_WT_ATAC_Consensus_Peaks.bw 1.1 Mb (ftp)(http) BW
GSE159886_ASXL1_WT_ChromHMM_States.bw 2.6 Mb (ftp)(http) BW
GSE159886_ASXL1_WT_H2AK119ub_Consensus_Peaks.bw 259.9 Kb (ftp)(http) BW
GSE159886_ASXL1_WT_H3K27ac_Consensus_Peaks.bw 748.9 Kb (ftp)(http) BW
GSE159886_ASXL1_WT_H3K27me3_Consensus_Peaks.bw 162.2 Kb (ftp)(http) BW
GSE159886_ASXL1_WT_H3K4me1_Consensus_Peaks.bw 553.4 Kb (ftp)(http) BW
GSE159886_ASXL1_WT_H3K4me3_Consensus_Peaks.bw 374.9 Kb (ftp)(http) BW
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