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Series GSE15935 Query DataSets for GSE15935
Status Public on May 03, 2009
Title Expression data from 'naïve' and HVC-replicon containing Huh7 cells (Clone A cells)
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Cyclophilin binding drugs, NIM811 and cyclosporin A (CsA), inhibit the replication of HCV replicon.
We investigated the mode of action of these drugs and identified host factors essential for HCV replication in a subgenomic replicon model.
 
Overall design Cultured Huh7 cell were treated with CsA or NIM811 at different concentrations. Cells were harvested after 12, 24 or 48 hours. The extracted mRNA were hybridized on Affymetrix U133 Plus 2 microarrays.
 
Contributor(s) Balabanis KA, Devay P, Wiedmann B
Citation(s) 19932913
Submission date May 03, 2009
Last update date Mar 25, 2019
Contact name Piroska Devay
E-mail(s) piroska.devay@novartis.com
Phone 6178717891
Organization name NIBRI
Department Infectious Disease
Lab Applied Sciences
Street address 500 Technology Sq
City Cambridge
State/province MA
ZIP/Postal code 02139
Country USA
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (82)
GSM399780 Huh7 cells cultured for 12 hours rep1
GSM399781 Huh7 cells cultured for 12 hours rep2
GSM399782 Huh7 cells cultured for 12 hours rep3
Relations
BioProject PRJNA116979

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE15935_RAW.tar 658.8 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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