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| Status |
Public on Sep 23, 2020 |
| Title |
Functional regeneration and repair of tendons using biomimetic scaffolds loaded with recombinant Periostin |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Although the biological events that modulate tendon embryonic development are widely studied, how they orchestrate postnatal tendon maturation that is similar to tendon regeneration is still largely unknown
For molecular profiling of tendon maturation, we performed mRNA microarray analyses of total rat tendon tissue harvested from normal neonatal and 6-8w Achilles’ tendons and identified meaningful genes in down-regulated group
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| Overall design |
Tendon tissues from the neonatal (1day) and 6-8 week rats were harvested.Then total RNA was extracted using Trizol reagen, and following labeling, fragmented cDNA was hybridized for 16 h at 45 oC on GeneChip Affymetrix Rat Transcriptome Array 1.0 (Affymetrix))
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| Contributor(s) |
Liu Y, Wang Y |
| Citation(s) |
37872152 |
| |
| Submission date |
Sep 22, 2020 |
| Last update date |
Nov 02, 2023 |
| Contact name |
yu Wang |
| E-mail(s) |
xinghuawangyu@sina.com
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| Phone |
+8618311372168
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| Organization name |
Peking University
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| Department |
Peking University School and Hospital of Stomatology
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| Lab |
Laboratory of Biomimetic Nanomaterials
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| Street address |
22 South Zhongguancun Street, Haidian District
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| City |
Beijing |
| State/province |
Beijing |
| ZIP/Postal code |
100081 |
| Country |
China |
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| Platforms (1) |
| GPL22388 |
[RTA-1_0] Affymetrix Rat Transcriptome Array 1.0 [transcript (gene) CSV version] |
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| Samples (6)
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| GSM4798121 |
Achilles tendon at P 1d,biological rep1 |
| GSM4798122 |
Achilles tendon at P 1d,biological rep2 |
| GSM4798123 |
Achilles tendon at P 1d,biological rep3 |
| GSM4798124 |
Achilles tendon at P 6-8w,biological rep1 |
| GSM4798125 |
Achilles tendon at P 6-8w,biological rep2 |
| GSM4798126 |
Achilles tendon at P 6-8w,biological rep3 |
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| Relations |
| BioProject |
PRJNA664945 |
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