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| Status |
Public on Sep 07, 2021 |
| Title |
Gene expression of S100A10 knocked down human breast cancer cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
The expression level of S100A10 was much higher in the CD44+ cancer cells metastasized to the liver than those at the primary site in the breast cancer patient-derived tumor xenograft mice. Expression level of S100A10 increased by the oncoprotein, PML/RARĪ± and RAS, and its higher expression is linked to worse outcome in a number of cancer types including breast cancers
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| Overall design |
Human breast cancer MDA-MB-231 cells were infected with lentivirus encoding shRNA sequences against S100A10. Two different shRNA sequences (shS100A10-1, shS100A10-5) that effectively knockdown S100A10 were used. Analyses were duplicated.
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| Contributor(s) |
Shimono Y, Nishimura T, Gotoh N |
| Citation(s) |
32976661 |
| |
| Submission date |
Sep 04, 2020 |
| Last update date |
Dec 08, 2021 |
| Contact name |
Nishimura Tatsunori |
| E-mail(s) |
tatsunori323@med.nagoya-u.ac.jp
|
| Organization name |
Nagoya University
|
| Department |
Graduate School of Medicine
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| Lab |
Division of Cancer Biology
|
| Street address |
65 Tsurumai-cho, Showa-ku
|
| City |
Nagoya |
| State/province |
Aichi |
| ZIP/Postal code |
466-8550 |
| Country |
Japan |
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| Platforms (1) |
| GPL23159 |
[Clariom_S_Human] Affymetrix Clariom S Assay, Human (Includes Pico Assay) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA661489 |
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