|
| Status |
Public on Aug 25, 2020 |
| Title |
Next Generation Sequencing Facilitates Quantitative Analysis of Control and rhCYGB treated liver transcriptomes [DDC] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Purpose: The goal of this study is to investigate the effect of recombinant human Cytoglobin (rhCYGB) on liver fibrosis induced by DDC diet in mice.
Method: mRNA profiles of liver tissue of DDC-control mice and liver tissue of DDC-rhCYGB treated mice treated were generated by deep sequencing.
Results: The RNA-seq data confirmed that extracellular matrix-encoding genes and fibrosis-related genes were down-regulated by the His-CYGB treatment.
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| |
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| Overall design |
mRNA profiles of liver tissues with or without rhCYGB treatment
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| |
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| Contributor(s) |
Kawada N, Thuy LT, Dat NQ |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Aug 24, 2020 |
| Last update date |
Aug 25, 2020 |
| Contact name |
Le Thi Thanh Thuy |
| E-mail(s) |
thuylt1977@yahoo.com
|
| Phone |
+81666453905
|
| Organization name |
Osaka City University, Graduate School of Medicine
|
| Department |
Department of Hepatology
|
| Street address |
1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan
|
| City |
Osaka |
| State/province |
Osaka |
| ZIP/Postal code |
545-8585 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE156780 |
Next Generation Sequencing Facilitates Quantitative Analysis of Control and rhCYGB treated liver and HHSteC transcriptomes |
|
| Relations |
| BioProject |
PRJNA659011 |
| SRA |
SRP278648 |
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