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Status |
Public on Oct 04, 2022 |
Title |
Sequencing analysis of immunopanned embryonic and early postnatal mouse RGCs |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
We report the genome-wide RNA sequencing changes to isolated retinal ganglion cells (RGCs) from immunopanned embryonic day 18 (E18) and early postnatal (P5) wildtype mouse retinas. We report the transcriptomic change associated with RGCs in a survival and regenerative state, and use gene-set enrichment analysis (GSEA) to predict the upstream transcription factors likely regulating these observed changes.
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Overall design |
Time-course analysis of RGC transcriptomes in embryonic versus postnatal states.
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Contributor(s) |
Kawaguchi R, Shah SH, Trakhtenberg E, Yin Y, Coppola G, Geschwind D, Benowitz LI, Goldberg JL |
Citation(s) |
36261683 |
Submission date |
Aug 16, 2020 |
Last update date |
Jan 03, 2023 |
Contact name |
Riki Kawaguchi |
E-mail(s) |
rkawaguchi@mednet.ucla.edu
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Phone |
4244424783
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Organization name |
University of California Los Angeles
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Department |
Department of Neurology and Department of Psychiatry
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Lab |
Informatics Center for Neurogenetics and Neurogenomics (ICNN).
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Street address |
760 Westwood Plaza, Room 37-420
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City |
Los Angeles |
State/province |
CA |
ZIP/Postal code |
90095-1759 |
Country |
USA |
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Platforms (1) |
GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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Samples (6)
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Relations |
BioProject |
PRJNA657405 |
SRA |
SRP277622 |