|
| Status |
Public on Feb 24, 2021 |
| Title |
CITE-seq (cellular indexing of transcriptomes and epitopes by sequencing) of WT and RAS mutant specimens from acute myeloid leukemia (AML) patients. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To understand the role of RAS mutations in AML, we performed CITE-seq on diagnosis specimens from WT and RAS mutant AML patients.
|
| |
|
| Overall design |
Cells were harvested from AML patients at diagnosis and subjected to CITE-seq analysis.
|
| Web link |
https://doi.org/10.1038/s43018-020-00126-z
|
| |
|
| Contributor(s) |
Stevens B, Gillen A, Jordan C |
| Citation(s) |
33884374 |
| |
| Submission date |
Aug 11, 2020 |
| Last update date |
May 26, 2021 |
| Contact name |
Brett Stevens |
| E-mail(s) |
brett.stevens@ucdenver.edu
|
| Phone |
3037248231
|
| Organization name |
University of Colorado
|
| Lab |
Jordan Lab
|
| Street address |
12700 E 19th Avenue, Rm 10440C
|
| City |
Aurora |
| State/province |
CO |
| ZIP/Postal code |
80045 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (9)
|
| GSM4721197 |
Gene expression from wt patient #1 [wt1_GEX] |
| GSM4721198 |
Antibody-derived tags from wt patient #1 [wt1_ADT] |
| GSM4721199 |
Gene expression from hashed wt patients #2 and #3 [wt2_wt3_GEX] |
| GSM4721200 |
Antibody-derived tags from hashed wt patients #2 and #3 [wt2_wt3_ADT] |
| GSM4721201 |
Hashtag oligos from hashed wt patients #2 and #3 [wt2_wt3_HTO] |
| GSM4721202 |
Gene expression from RAS mutant patient #2 [mut2_GEX] |
| GSM4721203 |
Antibody-derived tags from RAS mutant patient #2 [mut2_ADT] |
| GSM4721204 |
Gene expression from RAS mutant patient #3 [mut3_GEX] |
| GSM4721205 |
Antibody-derived tags from RAS mutant patient #3 [mut3_ADT] |
|
| Relations |
| BioProject |
PRJNA656531 |
| SRA |
SRP277062 |
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