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| Status |
Public on Nov 08, 2020 |
| Title |
Tracheal aspirate transcriptomic and miRNA signatures of extreme premature birth with bronchopulmonary dysplasia |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We analyzed mRNA profiles in tracheal aspirates from 53 newborns receiving invasive mechanical ventilation. Twenty-six infants were extremely preterm diagnosed with BPD and twenty-seven were term babies receiving invasive mechanical ventilation for elective procedure. Specific mRNA signatures in TAs may serve as potential biomarkers for extreme prematurity and BPD pathogenesis.
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| Overall design |
We extracted RNA from 0.5 mL of tracheal aspirates from neonates without lung disease or with bronchopulmonary dysplasia. Transcriptomic analysis was performed by RNAseq. Raw data is not provided due to the agreement by Institutional Review Board (IRB).
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| Contributor(s) |
Oji-Mmuo C, Siddaiah R, Imamura Kawasawa Y, Silveyra P |
| Citation(s) |
33177681 |
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| Submission date |
Aug 11, 2020 |
| Last update date |
Nov 12, 2020 |
| Contact name |
Yuka Imamura Kawasawa |
| E-mail(s) |
yui102@psu.edu
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| Organization name |
Penn State University
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| Department |
College of Medicine, Pharmacology
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| Street address |
500 University Dr.
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| City |
Hershey |
| State/province |
PA |
| ZIP/Postal code |
17033 |
| Country |
USA |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (38)
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| GSM4720668 |
B5, bronchopulmonary dysplasia |
| GSM4720669 |
B6, bronchopulmonary dysplasia |
| GSM4720670 |
C7, no lung disease |
| GSM4720671 |
B8, bronchopulmonary dysplasia |
| GSM4720672 |
B9, bronchopulmonary dysplasia |
| GSM4720673 |
C10, no lung disease |
| GSM4720674 |
B11, bronchopulmonary dysplasia |
| GSM4720675 |
B13, bronchopulmonary dysplasia |
| GSM4720676 |
B14, bronchopulmonary dysplasia |
| GSM4720677 |
C15, no lung disease |
| GSM4720678 |
C16, no lung disease |
| GSM4720679 |
B18, bronchopulmonary dysplasia |
| GSM4720680 |
B19, bronchopulmonary dysplasia |
| GSM4720681 |
C20, no lung disease |
| GSM4720682 |
B21, bronchopulmonary dysplasia |
| GSM4720683 |
C22, no lung disease |
| GSM4720684 |
B25, bronchopulmonary dysplasia |
| GSM4720685 |
B26, bronchopulmonary dysplasia |
| GSM4720686 |
B29, bronchopulmonary dysplasia |
| GSM4720687 |
B30, bronchopulmonary dysplasia |
| GSM4720688 |
C31, no lung disease |
| GSM4720689 |
C32, no lung disease |
| GSM4720690 |
C33, no lung disease |
| GSM4720691 |
C34, no lung disease |
| GSM4720692 |
B35, bronchopulmonary dysplasia |
| GSM4720693 |
B36, bronchopulmonary dysplasia |
| GSM4720694 |
C38, no lung disease |
| GSM4720695 |
C39, no lung disease |
| GSM4720696 |
C40, no lung disease |
| GSM4720697 |
C41, no lung disease |
| GSM4720698 |
C43, no lung disease |
| GSM4720699 |
B44, bronchopulmonary dysplasia |
| GSM4720700 |
B45, bronchopulmonary dysplasia |
| GSM4720701 |
B46, bronchopulmonary dysplasia |
| GSM4720702 |
C47, no lung disease |
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| Relations |
| BioProject |
PRJNA656505 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE156028_NGSCSVBPDwCfirst.csv.gz |
1.2 Mb |
(ftp)(http) |
CSV |
| Raw data not provided for this record |
| Processed data are available on Series record |
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