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| Status |
Public on May 13, 2021 |
| Title |
Effect of platelets on 3D models of ovarian cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
A 3D multicellular model (MCM) of high grade serous ovarian cancer (HGSOC) consisting of primary human adipocytes, fibroblasts, and mesothelial cells co-cultured with HGSOC cell lines was used to examine the effect of platelets on the ovarian metastasis microenvironment.
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| Overall design |
RNA sequencing was performed on multicellular models with (n = 3) or without addition of platelets (n = 3) as well as co-cultures of mesothelial cells and fibroblasts (n = 3) and adipocyte monocultures (n = 1).
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| |
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| Contributor(s) |
Maniati E, Malacrida B, Nichols S, Pearce O |
| Citation(s) |
34189439 |
| |
| Submission date |
Aug 02, 2020 |
| Last update date |
Jul 08, 2021 |
| Contact name |
Eleni Maniati |
| E-mail(s) |
e.maniati@qmul.ac.uk
|
| Organization name |
Queen Mary University of London
|
| Department |
Barts Cancer Institute
|
| Lab |
Cancer and Inflammation
|
| Street address |
John Vane Science Centre, Charterhouse Square
|
| City |
London |
| ZIP/Postal code |
EC1M 6BQ |
| Country |
United Kingdom |
| |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA650239 |
| SRA |
SRP275531 |
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