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| Status |
Public on Jul 31, 2020 |
| Title |
Paternal nicotine exposure promotes hepatic fibrosis in offspring |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Paternal nicotine exposure can alter phenotypes in future generations. To explore whether paternal nicotine exposure affects the hepatic repair to chronic injury which would lead to hepatic fibrosis in offspring, we establish a paternal effect model based on nicotine exposure in mice.
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| Overall design |
RNA profiles of the liver of 8-weeks old F1-C(whose father were treated with saline) and F1-N(whose father were treated with nicotine) mice were generated by RNA sequencing.
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| |
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| Contributor(s) |
Qiao Z, Zhang D |
| Citation missing |
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| |
| Submission date |
Jul 28, 2020 |
| Last update date |
Aug 02, 2020 |
| Contact name |
Dong Zhang |
| E-mail(s) |
zhangdong1025@126.com
|
| Organization name |
shanghaijiaotong university
|
| Street address |
dongchuan road
|
| City |
Shanghai |
| ZIP/Postal code |
200240 |
| Country |
China |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA649278 |
| SRA |
SRP274002 |
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