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Status |
Public on Jun 10, 2021 |
Title |
The clinical significance of regulatory variants at the GDF5 locus in joint disease |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
Summary |
Genetic variants in cis-regulatory regions of GDF5 can lead to common joint diseases with high degrees of joint specificity.
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|
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Overall design |
Examination of open chromatin regions in multiple different growth plates (proximal vs distal femur, tibia) and acetabulum at E67
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Contributor(s) |
Capellini TD, Richard D, Young M, Muthuirulan P |
Citation(s) |
34230488 |
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Submission date |
Jun 25, 2020 |
Last update date |
Jul 16, 2021 |
Contact name |
Terence D Capellini |
E-mail(s) |
drichard@g.harvard.edu, tcapellini@g.harvard.edu
|
Phone |
6173010673
|
Organization name |
Harvard Univserity
|
Department |
Human Evolutionary Biology
|
Lab |
Capellini
|
Street address |
11 Divinity Avenue
|
City |
Cambridge |
State/province |
MA |
ZIP/Postal code |
02138 |
Country |
USA |
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|
Platforms (1) |
GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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Samples (5)
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Relations |
BioProject |
PRJNA641883 |
SRA |
SRP268820 |