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| Status |
Public on Nov 30, 2020 |
| Title |
Metabolic programming drives proximal tubule differentiation and kidney dysfunction |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Renal disease development is poorly understood, mostly because the kidney is made up of more than 20 different cell types, each of them with specific function and complex interaction. Here, we used single cell RNA sequencing to resolve cell-type specific and cell fraction changes
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| Overall design |
Single-cell RNA-seq of engineered human kidney organoids
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| Web link |
https://doi.org/10.1016/j.cmet.2020.11.011
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| Contributor(s) |
Park J, Dhillon P, Hurtado C, Li L, Huang S, Kang H, Shrestra R, Chatterjee S, Prado P, Han S, Liu H, Xin S, Bartmanov K, Romero JP, Prosper F, Li M, Pei L, Kim J, Montserrat N, Susztak K |
| Citation(s) |
33301705 |
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| Submission date |
Jun 18, 2020 |
| Last update date |
Mar 07, 2021 |
| Contact name |
Juan Pablo Romero |
| E-mail(s) |
juanpablo.romerorioj@10xgenomics.com
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| Organization name |
10x Genomics
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| Department |
Computational Biology
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| Street address |
6230 Stoneridge Mall Rd
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| City |
Pleasanton |
| State/province |
CA |
| ZIP/Postal code |
94588 |
| Country |
USA |
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| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (1) |
| GSM4625992 |
Engineered Human Kidney Organoids (scRNA-seq) |
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| Relations |
| BioProject |
PRJNA640369 |
| SRA |
SRP267854 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE152765_RAW.tar |
64.8 Mb |
(http)(custom) |
TAR (of H5) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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