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| Status |
Public on Dec 02, 2022 |
| Title |
Functional genomic analyses of iPSC-derived pancreatic progenitor cells |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
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| Summary |
The goal of this study is to molecularly characterize regulatory variation in pancreatic progenitor cells (PPC). Here, we derived PPC from iPSCs of nine iPSCORE individuals (DeBoever et al., 2017; Panopoulos et al., 2017), and generated RNA-seq, ATAC-seq, scRNA-seq, and snATAC-seq. We strive to understand the role of functional genetic variation during fetal pancreatic development that later give rise to adult pancreatic diseases.
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| Overall design |
Transcriptome and chromatin accessibility maps of iPSC-PPCs.
**Submitter states that the raw data will be available in dbGaP (phs000924)**
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| Web link |
https://doi.org/10.1101/2021.10.20.465206
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| Contributor(s) |
Frazer KA, D'Antonio M, Matsui H, Nguyen J |
| Citation(s) |
37903777 |
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| Submission date |
Jun 16, 2020 |
| Last update date |
Jun 08, 2024 |
| Contact name |
Kelly Ann Frazer |
| E-mail(s) |
kafrazer@health.ucsd.edu
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| Phone |
650 288-9391
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| Organization name |
UC San Diego
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| Department |
Pediatrics
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| Lab |
Frazer
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| Street address |
9500 Gilman Drive
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| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92093 |
| Country |
USA |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (27)
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| Relations |
| BioProject |
PRJNA639821 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE152610_RAW.tar |
1.6 Gb |
(http)(custom) |
TAR (of BED, MTX, NARROWPEAK, TSV, TXT) |
| Processed data provided as supplementary file |
| Raw data not provided for this record |
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