|
| Status |
Public on Jun 03, 2020 |
| Title |
The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Utilizing single cell RNA sequencing, we demonstrated multiple time-anchored, cell-type specific events that are key to understand clinical features of sepsis.
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| |
|
| Overall design |
Wild type mouse kidneys were harvested and used for single cell RNAseq to examine baseline gene expression patterns across 0,1,4,16,27,36, and 48 hour timepoints after endotoxin (LPS) administration.
Library kit used for this dataset: Chromium Single Cell 3' Reagent Kits V2 was used with read1 L=26 and read2 L=91 configuration.
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| |
|
| Contributor(s) |
Janosevic D, Hato T, McCarthy T |
| Citation(s) |
33448928, 38954486 |
| |
| Submission date |
Jun 02, 2020 |
| Last update date |
Sep 30, 2024 |
| Contact name |
Takashi Hato |
| Organization name |
Indiana University School of Medicine
|
| Department |
Nephrology and Hypertension
|
| Lab |
Hato/Dagher Lab
|
| Street address |
950 W Walnut Street
|
| City |
Indianapolis |
| State/province |
IN |
| ZIP/Postal code |
46202 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (7)
|
|
| Relations |
| BioProject |
PRJNA636783 |
| SRA |
SRP265634 |
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