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Series GSE151039 Query DataSets for GSE151039
Status Public on Jun 15, 2020
Title Assessment of transcriptional ERa activity following exposure to 17a-E2 and 17b-E2
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary The study shows that, regardless of dose, both estrogens elicit nearly identical ERa activity
 
Overall design U2OS Cells were transfected with ERa and were exposed to vehicle, 17a-E2 (10nM & 100nM), or 17b-E2 (10nM) for 24 hours in preparation for RNA and ChIP sequencing analyses
 
Contributor(s) Stout M, Hawse J, Freeman W, Hadad N, Mann S
Citation(s) 33289482
Submission date May 22, 2020
Last update date Jan 04, 2021
Contact name Niran Hadad
E-mail(s) niranhadad@gmail.com
Phone 5802358620
Organization name The Jackson Laboratory
Street address 5 Bloomfield Rd, Unit A
City BAR HARBOR
State/province Maine
ZIP/Postal code 04609
Country USA
 
Platforms (1)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (26)
GSM4564692 U2OS Cells - ER alpa construct - 10nM 17alpha E2 - rep 1 [ChIP-Seq]
GSM4564693 U2OS Cells - ER alpa construct - 10nM 17alpha E2 - rep 2 [ChIP-Seq]
GSM4564694 U2OS Cells - ER alpa construct - 10nM 17alpha E2 - rep 3 [ChIP-Seq]
Relations
BioProject PRJNA634479
SRA SRP262887

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE151039_ERa100nM17a_CallPeak_peaks.txt.gz 914.8 Kb (ftp)(http) TXT
GSE151039_ERa10nM17a_CallPeak_peaks.txt.gz 861.5 Kb (ftp)(http) TXT
GSE151039_ERa10nM17b_CallPeak_peaks.txt.gz 915.0 Kb (ftp)(http) TXT
GSE151039_ERaRNAseqHg19AlignedNormalizedCounts.csv.gz 1.9 Mb (ftp)(http) CSV
GSE151039_ERaVEH_CallPeak_peaks.txt.gz 298.4 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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