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Status |
Public on Oct 27, 2020 |
Title |
Evolution of advanced chronic lymphoid leukaemia unveiled by single-cell transcriptomics: a case study |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Characterization of the transcriptional changes occurring at the single-cell level during the progression of a chronic lymphoid leukaemia treated with Rituximab, Fludarabine and Cyclophosphamide.
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Overall design |
Single-cell RNA-seq library from peripheral blood cells of a subject with chronic lymphoid leukaemia; samples at diagnosis and relapse were separatly barcoded and pooled; single-cell captured using 10x Chromium and subjected to high-throughput sequencing.
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Contributor(s) |
Barozzi I, Ostasov P, Caputo VS, Datta A, Piazza P, Holubova M |
Citation(s) |
33194728 |
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Submission date |
May 20, 2020 |
Last update date |
Jan 26, 2021 |
Contact name |
Iros Barozzi |
E-mail(s) |
iros.barozzi@meduniwien.ac.at
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Organization name |
Medical University Vienna
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Street address |
Borschkegasse 8a
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City |
Vienna |
ZIP/Postal code |
1090 |
Country |
Austria |
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Platforms (1) |
GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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Samples (1) |
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Relations |
BioProject |
PRJNA634108 |
SRA |
SRP262481 |