|
| Status |
Public on Aug 10, 2020 |
| Title |
Neutrophil extracellular traps mediate articular cartilage damage and enhance the immunogenicity of cartilage components in rheumatoid arthritis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
This study invesigates the effects of neutrophil extracellular traps (NETs) on articular cartilage degredation and resulting autoimmune responses in rheumatoid arthritis.
|
| |
|
| Overall design |
This dataset includes bulk RNA sequencing of fibroblast-like synoviocytes (FLS) that were treated with NETs for 48 hours.
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| |
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| Contributor(s) |
Carmona-Rivera C, Carlucci PM, Goel RR, James E, Brooks SR, Rims C, Hoffman V, Fox DA, Buckner JH, Kaplan MJ |
| Citation(s) |
32484790 |
| Submission date |
May 13, 2020 |
| Last update date |
Aug 10, 2020 |
| Contact name |
Stephen R Brooks |
| E-mail(s) |
stephen.brooks@nih.gov
|
| Organization name |
NIAMS/NIH
|
| Department |
Biodata Mining and Discovery Section
|
| Street address |
50 SOUTH DR, RM 1140
|
| City |
Bethesda |
| State/province |
MD |
| ZIP/Postal code |
20814 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA632502 |
| SRA |
SRP261405 |
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