|
| Status |
Public on Apr 21, 2021 |
| Title |
Temporal, spatial, and genetic constraints contribute to the patterning and penetrance of murine Neurofibromatosis-1 optic glioma |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Contributing factors to pediatric glioma formation
|
| |
|
| Overall design |
TVZ neuroglial progenitor cells (NPCs) were analyzed over the course of mouse brain development. FACS-isolated progenitors were assessed for functional and molecular differences. The impact of different germline Nf1 mutations on TVZ NPC properties was analyzed using genetically engineered mice.
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| |
|
| Contributor(s) |
Brossie NM, Thondapu S, Cobb OM, Gutmann DH |
| Citation(s) |
33080011 |
| |
| Submission date |
May 06, 2020 |
| Last update date |
Apr 21, 2021 |
| Contact name |
David Gutmann |
| Organization name |
Washington University in St Louis
|
| Department |
Neurology
|
| Lab |
NF Center
|
| Street address |
660 S Euclid Ave
|
| City |
St Louis |
| State/province |
MO |
| ZIP/Postal code |
63110 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL21493 |
Illumina HiSeq 3000 (Mus musculus) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA631206 |
| SRA |
SRP260661 |
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