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| Status |
Public on Oct 13, 2021 |
| Title |
MicroRNA-21-induced loss of Junctional Adhesion Molecule-A promotes activation of oncogenic pathways, progression and metastasis in colorectal cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Junctional adhesion molecules (JAMs) play a critical role in cell-cell interactions, cell permeability, polarity and migration. Gene expression and proteomic assays were used to define down-stream effectors of JAM-A dysregulation in colorectal cancer.
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| |
|
| Overall design |
RNA was extracted from JAM-A knockdown and ctrl cell lines (3 ctrl, 3 shRNA)
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| |
|
| Contributor(s) |
Valeri N |
| Citation(s) |
34226680 |
| |
| Submission date |
Apr 30, 2020 |
| Last update date |
Oct 13, 2021 |
| Contact name |
Luciano Cascione |
| E-mail(s) |
luciano.cascione@ior.usi.ch
|
| Organization name |
IOR
|
| Department |
Lymphoma & Genomics Research Program
|
| Street address |
Via Chiesa 5
|
| City |
Bellinzona |
| State/province |
Ticino |
| ZIP/Postal code |
6500 |
| Country |
Switzerland |
| |
|
| Platforms (1) |
| GPL19956 |
NanoString nCounter human PanCancer Pathways Panel |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA629564 |
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