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Series GSE148937 Query DataSets for GSE148937
Status Public on Apr 21, 2020
Title Targeted next generation sequencing of transcriptomes from human treatment-naïve patient-derived prostate tissues, organoids, and organoid-derived cells (unaffected and tumor counterparts)
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Human prostate mRNA profiles of organoids, cells, and tissues were generated by targeted next generation sequencing from three patients using Illumina® TruSeq Stranded mRNA prep kit.
Overall design Purpose: To examine the genome-wide expressions using targeted next generation sequencing (NGS) in novel patient-derived organoids and organoid-derived cells versus their corresponding human tissue specimens and whole-transcriptome sequencing on a number of prostate cancer patients. We aim to compare the novel patient-derived organoids and organoid-derived cells with their corresponding tissues (unaffected and tumor parts) to demonstrate the faithfulness of this model. In addition, we aim to explore the genomic profiles that exemplify the molecular landscape of Lebanese prostate cancer patients and identify lead targets that could be implemented for personalized treatments of this disease.
Contributor(s) Al-Sayegh M, Abou-Kheir W, Bahmad H
Citation(s) 34820005
Submission date Apr 20, 2020
Last update date Dec 07, 2021
Contact name Wassim Abou-Kheir
Phone +96176994308
Organization name American University of Beirut
Department Department of Anatomy, Cell Biology, and Physiological Sciences
Street address Bliss St. DTS Bldg.
City Beirut
ZIP/Postal code 1107
Country Lebanon
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (16)
GSM4486297 P2A
GSM4486298 P3A
GSM4486299 P4A
BioProject PRJNA626585
SRA SRP257513

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE148937_RAW.tar 3.4 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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