|
| Status |
Public on Mar 20, 2020 |
| Title |
mTORC2/Rac1 pathway predisposes cancer aggressiveness in IDH1-mutated glioma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The present study aims to investigation alterations in the transcriptional profile when cells acquire pathogenic IDH mutants
|
| |
|
| Overall design |
U251 MG cells were infected with lentivirus with IDH1 R132C or IDH1 R132H coding sequences. Cells were harvested and proceeded for mRNA sequencing analysis
|
| |
|
| Citation(s) |
32224866 |
| |
| Submission date |
Mar 19, 2020 |
| Last update date |
Jun 19, 2020 |
| Contact name |
Chunzhang Yang |
| Organization name |
NCI
|
| Department |
NOB
|
| Street address |
37 Convent Dr.
|
| City |
Bethesda |
| State/province |
Maryland |
| ZIP/Postal code |
20892 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA613452 |
| SRA |
SRP253336 |
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